Personalized medicine for a multi-site group — with one standard at every clinic
iksa is the harness for n‑of‑1 medicine. Your medical lead reads any clinic’s coronary CT decision in its doctor’s words, and a patient hears the same plan at all your doors.
A protocol can’t make two scanners agree, so it settles how a report gets read and what its band earns
You answer for doctors at clinics you don’t sit in, and each patient’s trial of one holds only if a scan at your newest clinic can be read beside one from your first. One set of protocols is how a result comes to mean the same thing at each clinic.
- Calcium scoreThe same 15 donated hearts read a median of 332 on one vendor’s scanner and 469 on another’s in Radiology, and MESA’s back-to-back scans differed by about 20%. So your protocol names the acquisition and reconstruction every center uses. Once, before a statin, because statins promote coronary calcification and a higher repeat can mislead.
- Vessels and percentileIn MESA the vessel count added to the score while percentile showed no trend once the absolute band was set. So 73rd or 69th doesn’t move the plan, and a third vessel belongs in your protocol or the note. On the same report as the score.
- Coronary CT angiographyIn JCCT, readers agreed closely on CAD-RADS stenosis and only fairly on high-risk plaque, which makes that the call to send for a second read. CAD-RADS 2.0 offers several plaque-burden methods, and you name one. When the score or the history calls for it, with follow-up kept on one vendor.
- ApoB and antiplatelet therapyYour group writes one ApoB target for each band. Low-dose antiplatelet therapy is where good doctors split: MESA’s modeled numbers in Circulation favor it under 70 from a calcium score of 100 when bleeding risk isn’t high, and USPSTF recommends against starting at 60 or older, so the group picks and writes down why. ApoB three months after a statin starts, then at each review, with Lp(a) once, as the 2026 ACC/AHA guideline recommends for every adult.
Six points and one vessel separate these two patients, and the group had written their plan before either scan
Patient X’s 146 and Patient Y’s 152 differ by less than MESA’s back-to-back scans did, so Patient Y’s doctor noted the third vessel and started what a colleague at your first clinic had started.
Show us what your protocol tells a doctor in their first month at your newest clinic when a calcium score lands in the middle band.
Request a walkthroughRequest a walkthrough for a multi-site groupPatients assume the same medicine behind every door with your name on it, and your sites were built to run themselves
A sponsor pays for sameness because its results have to pool. No payer asks your group for that, so the standard is one your group chooses to hold.
Core lab
Every scan in a multicenter trial is read one way, in one place. Your patients go to whichever center is nearest, so one report prints a CAC-DRS category with the vessels named, and the next prints a score and a percentile.
Site activation
Your newest doctor starts seeing patients in the first week and learns what the group does with an A2 by asking a colleague, at a stage when a trial site wouldn’t yet have enrolled anyone.
Monitoring
A trial’s monitor visits each site to see how its protocol runs, and your group sees it when a patient moves between two clinics and the second doctor asks why the plan differs.
Safety reporting
One statin plan started at every clinic comes back as muscle aches at each of them. A sponsor pools what its sites report and tells them all when something turns up or a label changes, while each of your clinics learns it on its own.
The patient’s plan was written at your newest clinic, and whichever clinic draws their next ApoB, the doctor there opens the same note
With your group set up as one clinic, the harness knows the patient from one record across the sites that chart in one system, so a new site on that system is configuration, and the doctor they see still decides.
Your medical lead reads an A2 decision from a clinic they rarely visit in the words of the doctor who made it
Clinical Intelligence sets out what was decided on the patient’s 152 from that doctor’s note, so the lead can see in one chart whether that doctor held to the group’s plan or wrote down why not. It grades nobody, so whether a departure was sound stays the lead’s reading.
Clinical Intelligence: clinical AI and lab trackingA nurse in their first month at the newest clinic has patients’ ApoB by status, and practice questions get drafts from your approved answers
Agentic CRM drafts from one set of approved answers across your clinics, while anything about a patient’s statin or their target goes to a person. When your group changes an answer, the next draft at any clinic uses the new one, and someone on your team still approves or edits it before it goes.
Agentic CRM: scheduling and follow-upWhat the patient is told about ApoB under 70 comes from their record, so it doesn’t change with the clinic they walk into
Patient AI explains what the doctor at the newest clinic wrote, and if the patient next sees a colleague at the first clinic, that colleague is reading the same note.
Patient AI: the treatment companion
A research group’s first question to a multi-site group would be whether a scan means the same thing at each clinic
Your written protocol, the notes that departed from it and the center printed on each report answer part of that. With identifiers removed, each patient’s consent and an ethics review, a first study could ask how much of what follows an A2 comes from the patient and how much from the clinic. How a first study would separate patient from clinic →
What the person answering for every clinic asks first
If the group writes the protocol, is the call still mine?
Still yours.A plan counts here because a doctor wrote it in a note, so nothing holds you to the group’s protocol except the group. Depart from it and your reason sits in that same note, where a colleague or your medical lead can read it.
Will it show me which clinic is drifting?
Chart by chart.iksa keeps no scoreboard of your clinics and doesn’t grade a doctor against your protocol. Your medical lead asks one patient’s record what was decided and on what, and gets that doctor’s note. A count across a whole clinic is still yours to run.
A patient is seen at two of our clinics. Which record is the real one?
One, if both chart in one system.We’d set your group up as one clinic on iksa, so a patient seen at two sites on the same EHR has one record, with a CT report from one and a note from the other, in date order. A patient also charted on another system stays two records. iksa puts no site stamp on a record, so the report and the note say where a scan was done.
What does a new site start with?
Configuration.iksa sets up its doctors and nurses by role, and they start on the records, the approved answers and the lab checks your other clinics already use, with nothing to move when it charts in the same system. What they still need from you is the protocol itself. One clinic on iksa keeps one time zone, one set of hours and one emergency number, so tell us if a site sits outside them.
Can iksa make our CT reads the same across sites?
Not the scanners.iksa keeps each CT report on file and takes what the doctor wrote about it, so two scanners stay two scanners. Your protocol can ask every center for the same acquisition and the same CAC-DRS and CAD-RADS reporting.
Each clinic came with its own EHR. Must we merge them first?
No, start with the protocol.Not to agree on a protocol, though what each clinic gets differs. A clinic on the EHR we connect to comes through that connection. Any other sends in patients one folder at a time, each its own record as of the day it’s sent and out of Patient AI’s reach until that clinic has a connection.
Can a nurse at one clinic pick up a patient from another?
By role, not by site.Access follows the role and not the site, so a nurse covering your first clinic can open a patient from your newest, and what the nurse does on a flagged card is logged with their name and the time.
What is n‑of‑1 medicine?All practicesiksa beside your EHRProtocol management softwareWhat iksa adds
Take one protocol across two of your clinics, and we’ll ask whether a report from either one gets the same plan
Bring a protocol you run. We’ll walk one patient through it.